Efficacy and safety of fixed-ratio combination of GLP-1 RA plus BI in type 2 diabetes mellitus: a network meta-analysis

AUTHORS: Shah R., Sayre T., Thomas J., Murray E., Brulle-Wohlhueter C., Shaunik A.
CONFERENCE: IDF Congress 2017
DATE: December 4-8, 2017.


This review aimed to better understand the safety and efficacy of FRCs of GLP-1 RAs and basal insulin (BI) in comparison with BI, GLP-1 RA, basal-bolus insulin, premix insulin, and free combination GLP-1 RA and BI via a systematic literature review and Bayesian NMA of patients with type 2 diabetes (T2D) who are inadequately controlled on insulin or a GLP-1 RA alone