DRE’s Medical Strategy Advisory Board (MSAB) advises DRE on the convergence between expert AI-enabled technology in healthcare and the exponential growth of clinical information. DRE is dedicated to applying sophisticated data science with advanced AI to generate quicker, deeper, more nuanced regulatory-grade scientific and clinical insights for the betterment of patient outcomes and the MSAB is a steering committee governance Board to ensure that our mission is achieved.
Ameet Nathwani MD, MRCP, DipPharmMed, MBA
With more than 25 years of experience in the pharmaceutical industry, Dr. Nathwani was most recently an Executive Committee member at Sanofi AG, as Chief Medical Officer, Head of Medical and Chief Digital Officer, responsible for enhancing Sanofi’s strategy to integrate digital technologies and medical science to ultimately improve patient outcomes.
Prior to joining Sanofi, Dr. Nathwani was the Global Head of Medical Affairs, Novartis Pharma AG and served as a member of the Pharma Executive Committee, where he led the establishment of a Real-World Evidence Center of Excellence and Digital Medicine capability. Over his 11 years at Novartis, Dr. Nathwani held a number of senior development and commercial positions including the Global Head of the Critical Care Business Franchise and Senior Vice President, Global Development Head of the Cardiovascular and Metabolic Franchise.
Prior to joining Novartis, Dr. Nathwani held senior roles in R&D roles in GlaxoSmithKline, SmithKline Beecham, and Glaxo Group Research in both the UK and US. Dr. Nathwani graduated in medicine in London, specialized in cardiology and intensive care medicine, and holds a Master's in Business Administration.
Calum MacRae, MD, PhD, BSc
Dr. MacRae is Vice-Chair for Scientific Innovation in the Department of Medicine at Brigham and Women’s Hospital (BWH), an Associate Professor of Medicine at Harvard Medical School, and an expert member of BWH’s Cardiovascular Genetics Program, which comprehensively evaluates, diagnoses and manages care for inherited cardiac disorder patients. In addition, he is a leading investigator at the BWH Genomics Center.
Dr. MacRae received his medical degree from the University of Edinburgh College of Medicine. He completed two internal medicine residency programs: one at Wellcome Trust Centre for Neuroimaging in London and the other at BWH. He then completed a fellowship in cardiovascular disease at Massachusetts General Hospital. Dr. MacRae is board certified in internal medicine and cardiovascular disease.
Dr. MacRae is a cardiologist and geneticist whose clinical interests include investigating new phenotypes and how research findings—including genomics discoveries—can be systematically implemented into clinical care. His research focuses on the biology and genomics of cardiovascular disease, specifically the biological basis of different arrhythmia susceptibilities. He holds five patents, has authored over 160 peer-reviewed publications and received research funding from the National Institutes of Health’s National Human Genome Research Institute.
Frank Rockhold, PhD, ScM, BA
Dr. Rockhold is a Professor of Biostatistics and Bioinformatics at Duke University Medical Center, Affiliate Professor of Biostatistics at Virginia Commonwealth University, and Managing Partner of HunterRockhold, Inc. His 40+-year career includes senior research positions at Lilly, Merck, and GlaxoSmithKline, where he retired as Chief Safety Officer and Senior Vice President of Global Clinical Safety and Pharmacovigilance. He has also held faculty appointments at six universities. Dr. Rockhold served for 9 years on the board of directors of the non-profit CDISC, most recently as Chairman, and is past president of the Society for Clinical Trials. He is a past member of the PCORI Clinical Trials Advisory Panel and is currently on the boards of the Frontier Science and Technology Research Foundation, Datavant, and an advisor to EMA.
Dr. Rockhold has diverse research interests and consulting experience in industry and academia including clinical trial design, data monitoring, benefit/risk, and most recently, safety and pharmacovigilance and has been a leader in the scientific community in promoting data disclosure and transparency in clinical research. Dr. Rockhold is widely published in major scientific journals across a wide variety of research topics.
Dr. Rockhold holds a BA in Statistics from The University of Connecticut, an ScM in Biostatistics from The Johns Hopkins University, and a PhD in Biostatistics from the Medical College of Virginia at Virginia Commonwealth University. Dr. Rockhold is an Elected Fellow of both the American Statistical Association and the Society for Clinical Trials, an Accredited Professional Statistician, PStat®, and a Chartered Statistician, CStat.
David Tovey, MB.ChB., FRCGP
Dr. Tovey is Co-Editor in Chief for the Journal of Clinical Epidemiology. He was Editor in Chief of The Cochrane Library for over 10 years, responsible for ensuring the quality and relevance of Cochrane Reviews and also for providing support for initiatives aimed at increasing their impact on clinical practice and health policy. He worked previously as Editorial Director for the BMJ Evidence Centre, which is the division of the BMJ Group that produces evidence-based resources for health professionals and the public. Dr. Tovey worked as a General Practitioner in urban practice in South London for 15 years until 2003 and is a Fellow of the UK Royal College of General Practitioners.
Michael Klag, MD, MPH
Dr. Klag is the former Dean of the Johns Hopkins Bloomberg School of Public Health and is chair of the Association of Schools of Public Health and chair of the NIH Advisory Board on Clinical Research.
Dr. Klag is an internist and epidemiologist who earned his medical degree at the University of Pennsylvania and his master’s in public health degree from the Johns Hopkins School of Hygiene and Public Health. Previously, he was Director of the Division of General Internal Medicine and was the first Vice Dean for Clinical Investigation at the Johns Hopkins School of Medicine.
Dr. Klag is a world-renowned kidney disease epidemiologist whose scientific contributions have been in the prevention and epidemiology of kidney disease, hypertension and cardiovascular disease. Dr. Klag directs one of the longest-running longitudinal studies in existence, the Precursors Study, which began in 1946. Dr. Klag is the author of more than 200 publications and was the Editor-in-Chief of the Johns Hopkins Family Health Book.