Reviews

DRE’s team of expert librarians and methodologists deliver high quality expedited and systematic reviews across the broad spectrum of available medical evidence.  Our rigorous systematic review process is based on a “PICO” search strategy (Patient, Intervention, Comparators, Outcome) and evidence included in the evidence reviews can be weighted for relevance according to the PICO selected. Once the relevant evidence has been identified DRE’s proprietary Digital Outcome Conversion (DOC) process is used to extract data from a set of full-text articles, which are then organized into highly structured data sets.   All extracted data can be summarized in text or table format, enabling a fully transparent and reproducible understanding of the individual data by referring back to individual referenced papers and specific data elements. From this rich data-source, our expert team provides impactful and comprehensive review services to help clients make important evidence-based decisions.

  • Systematic Literature Reviews (SLR): Our team of librarians and methodologists systematize, synthesize and critically analyze the most relevant scientific literature to address your healthcare research question. The SLRs can be constructed to include the following:
    • Intervention/Prevention (e.g., Comparative Effectiveness) Safety): Analyze clinical, safety and cost-effectiveness of comparator treatments.
    • Epidemiologic: Understand disease distribution, risk factors, treatment patterns and impact, comorbidities, burden-of-illness and other related factors.
    • Prognostic: Evaluate outcomes based on prognostic factors.
    • Diagnostic Accuracy: Compare standards of diagnosis through methodologically structured studies.
    • Service Delivery: Determine competitive and quality-driven healthcare service delivery models.
    • Economic Evaluation: Compare optimal allocation of resources of selected interventions.
  • Landscape Analysis: Review comprehensive, competitive landscape information to inform areas and phases of development.
  • Disease Opportunity Profiling: Assess therapeutic opportunities within specific disease areas and pathways.
  • Value Dossiers: Design well differentiated clinical, economic, and humanistic value propositions for ongoing updates or new products in a disease area.