Publications

Doctor Evidence (DRE) is a specialty evidence-based medicine (EBM) software platform and services company that provides EBM organizations with the most relevant medical evidence and sophisticated analytics to inform clinical care decisions. An innovator in technological advances to help the healthcare ecosystem find, synthesize and analyze data from public sources into actionable knowledge, the company’s dynamic platforms have been used and cited in peer-reviewed studies, conferences, and posters.

The articles, conference presentations and posters highlight the use of the DRE platforms to:

  • Automatically extract sentences pertaining to PICO elements through machine learning
  •  Use advanced search filters to provide literature surveillance
  •  Conduct transparent meta-analyses to inform treatment decisions
  •  Contribute 2 million data points from peer-reviewed articles, clinical research studies, conference proceedings, epidemiology statistics, and drug label data to IBM Watson
  •  Create and update evidence-based guidelines.

Using the analyses generated by DREs products and services, the DRE team supports high impact publication strategy, development and submission to leading journals and scientific congresses. DRE's software delivers content for industry-leading systematic review and scientific publications, including presentations and posters for EBM conferences.

DRE also partners with an extensive network of EBM, academic, and key opinion leaders and authors, including McMaster University and US Evidence-based Practice Centers (e.g., Brown University, Oregon Health & Science University). Our leading author and publication partners span the globe in all key areas, including diagnostic, treatment, epidemiological, risk factors, humanistic, and economic analysis.
Browse our library of peer-reviewed publications, conferences, and presentations.

PUBLICATIONS

Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline

AUTHORS: Brahmer JR, Lacchetti C, Schneider BJ, Atkins MB, Brassil KJ, Caterino JM, Chau I, Ernstoff MS, Gardner JM, Ginex P, Hallmeyer S, Holter Chakrabarty J, Leighl NB, Mammen JS, McDermott DF, Naing A, Nastoupil LJ, Phillips T, Porter LD, Puzanov I, Reichner CA, Santomasso BD, Seigel C, Spira A, Suarez-Almazor ME, Wang Y, Weber JS, Wolchok, and Thompson JA in collaboration with the National Comprehensive Cancer Network
Publication: Journal of Clinical Oncology
YEAR: 2018
Web-link: http://ascopubs.org/doi/full/10.1200/JCO.2017.77.6385
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Machine learning for identifying Randomized Controlled Trials: An evaluation and practitioner's guide

AUTHORS: Marshall IJ, Noel-Storr A, Kuiper J, Thomas J, Wallace BC
Publication: Wiley Online Library
YEAR: 2018
Web-link: http://onlinelibrary.wiley.com/doi/10.1002/jrsm.1287/full
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Screening for Lung Cancer: CHEST Guideline and Expert Panel Report

AUTHORS:Mazzone PJ, Silvestri GA, Patel S, Kanne JP, Kinsinger LS, Weiner RS, Soo Hoo G, Detterbeck FC
Journal: Screening for Lung Cancer: CHEST Guidelines and Expert Panel Report
YEAR: 2018
Web-link: http://journal.chestnet.org/article/S0012-3692(18)30094-1/pdf
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Effect of Dysphagia Screening Strategies on Clinical Outcomes After Stroke: A Systematic Review for the 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke

AUTHORS: Smith EE, Kent DM, Bulsara KR, Leung LY, Lichtman JH, Reeves MJ, Towfighi A, Whiteley WN, Zahuranec DB on behalf of the American Heart Association Stroke Council.
Journal: Stroke
YEAR: 2018
Web-link: http://stroke.ahajournals.org/content/early/2018/01/23/STR.0000000000000159
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Effect of Dysphagia Screening Strategies on Clinical Outcomes After Stroke: A Systematic Review for the 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke

AUTHORS: Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, Biller J, Brown M, Demaerschalk BM, Hoh B, Jauch EC, Kidwell CS, Leslie-Mazwi TM, Ovbiagele B, Scott PA, Sheth KN, Southerland AM, Summers DV, Tirschwell DL on behalf of the American Heart Association Stroke Council.
Journal: Stroke
YEAR: 2018
Web-link: http://stroke.ahajournals.org/content/early/2018/01/23/STR.0000000000000158
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Systematic Review for the 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults
A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.

AUTHORS: Reboussin D.M, Allen N. B., Griswold M.E., Guallar E., Hong Y., Lackland D.T., Miller ER 3rd, Polonsky T, Thompson-Paul A.M. and Vupputuri S.
Journal: Journal of the American College of Cardiology
YEAR: 2017
Web-link: http://www.onlinejacc.org/content/early/2017/11/04/j.jacc.2017.11.004
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Systematic Review for the 2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.

AUTHORS: Kusumoto F.M, Bailey K.R., Chaouki A.S., Deshmukh A.J., Gautam S., Kim R.J., Kramer D.B, Lambrakos L.K., Nasser N.H., Sorajja D.
Journal: Circulation
YEAR: 2017
Web-link: http://circ.ahajournals.org/content/early/2017/10/30/CIR.0000000000000550
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Pacing as a Treatment for Reflex-Mediated (Vasovagal, Situational, or Carotid Sinus Hypersensitivity) Syncope: A Systematic Review for the 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope.

AUTHOR: Chen, Y., Miller, A.L., Amy, Noseworthy, P.A., Slotwiner, D. J., Thiruganasambandamoorthy,V.
Journal: Journal of the American College of Cardiology
YEAR: 2017
Web-link: http://www.onlinejacc.org/content/early/2017/03/03/j.jacc.2017.03.004
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Evaluation of Clinical Endpoints as Surrogates for Survival in Patients Treated with Immunotherapies.

AUTHOR: Kaufman,H., Schwartz, L.H.,. William, W.N., Sznol, M, del Aguila, M., Whittington, C., Fahrbach, K,, Xu, Y., Masson, E., Dempster, S., and Vergara-Silva, A. L.
Journal: Journal of Clinical Oncology 35. (suppl; abstr e14557)
YEAR: 2017
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Respiratory syncytial virus hospitalization and mortality: Systematic review and meta-analysis.

AUTHOR: Stein, R.T., Bont, L.J., Zar, H., Polack, F.P., Park, C., Claxton, A., Borok, G., Butylkova, Y., and Wegzyn, C.
Journal: Pediatric Pulmonology. 2016 Oct 14. doi: 10.1002/ppul.23570.
YEAR: 2016
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Development of System-Level Performance Measures for Evaluation of Models of Care for Inflammatory Arthritis in Canada.

AUTHOR:Barber, C.E., Marshall, D.A., Mosher, D.P., Akhavan, P., Tucker, L., Houghton, K., Batthish, M., Levy, D.M., Schmeling, H., Ellsworth, J. and Tibollo, H.
Journal: The Journal of rheumatology (2016): jrheum-150839
YEAR: 2016
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Extracting PICO Sentences from Clinical Trial Reports using Supervised Distant Supervision.

AUTHOR: Wallace, B.C., Kuiper, J, Sharma, A, Marshall, I.J. and Zhu, M.B.
Journal: Journal of Machine Learning Research. (2016).
YEAR: 2016
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Recommendations for kidney disease guideline updating: a report by the KDIGO Methods Committee.

AUTHOR: Uhlig, K., Berns, J.S., Carville, S., Chan, W., Cheung, M., Guyatt, G.H., Hart, A., Lewis, S.Z., Tonelli, M., Webster, A.C. and Wilt, T.J.
Journal: Kidney international 89.4 (2016): 753-760.
YEAR: 2016
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Patient Outcomes of Hip Resurfacing Compared to Total Hip Arthroplasty: A Systematic Review.

AUTHOR: Pykerman, K., Frank, C., Noseworthy, T., Lorenzetti, D., Werle, J., Wasylak, T., Dick, D.A., O'Connor, G. and Marshall, D.
Journal: Value in Health 16.3 (2013): A217-A218.
YEAR: 2013
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Assessing Janus Kinase Inhibitor's Place in Therapy in Established Rheumatoid Arthritis Patients-From a Simplified Indirect Comparison Versus Tumor Necrosis Factor Inhibitors to a Bayesian Probability of Response-The Value Of Transparency.

AUTHOR: Ingham, M.P., Song, P., Cartier, S., Lawson-Remer, K. and Murray, E.
Journal: Arthritis and Rheumatism. Vol. 65. 111 River St, Hoboken 07030-5774, Nj Usa: Wiley-Blackwell, 2013. Presented at the 2013 Academy of Managed Care Pharmacy (AMCP) meeting, October 16-18 in San Diego, California.
YEAR: 2013
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Demonstration of an Online Tool to Assist Care Formulary Evidence-based Decision-making: Meta-analysis of Topical Prostaglandin Analog Efficacy.

AUTHOR: Kymes, S.M., Burk, C., Feinman, T., Williams, J.M. and Hollander, D.A.
Journal: Therapeutics and Clinical Risk Management, 2011; 7: 283–290. Published online 2011 July 12.
YEAR: 2011
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Cost-offset analysis: bimatoprost versus other prostaglandin analogues in open-angle glaucoma.

AUTHOR: Berenson, K.L., Kymes, S., Hollander, D.A., Fiscella, R., Burk, C. and Patel, V.D.
Journal: The American journal of managed care 17.9 (2011): e365-74.
YEAR: 2011
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PRESENTATIONS

Clinical Outcomes Associated with De-Escalation from Ticagrelor to Clopidogrel in Patients with Acute Coronary Syndrome

AUTHOR: Angiolillo D, Paek D, Shah R, Fazeli MS, Girotra S
CONFERENCE: ACC 2018
DATE: March 10-12, 2018.
See poster

Prevalence and Timing of De-Escalation Therapy from Ticagrelor to Clopidogrel in Acute Coronary Syndrome Patients: Results of a Meta-Analysis

AUTHOR: Angiolillo D, Paek D, Shah R, Sayre T, Clausel A, Girotra S
CONFERENCE: ACC 2018
DATE: March 10-12, 2018.
See poster

Network meta-analysis of iGlarLixi, a fixed-ratio combination GLP-1 RA and basal insulin, versus insulin premix

AUTHOR: Sayre T., Shah R., Thomas J., Murray E., Brulle-Wohlhueter C., Shaunik A., Perfetti R.
CONFERENCE: IDF Congress 2017
DATE: December 4-8, 2017.
See poster

Network meta-analysis of treatments for type 2 diabetes in patients inadequately controlled on oral antidiabetics

AUTHOR: Shah R., Sayre T., Thomas J., Murray E., Brulle-Wohlhueter C., Shaunik A.
CONFERENCE: IDF Congress 2017
DATE: December 4-8, 2017.
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Innovative AI-powered technologies to facilitate evidence dissemination to inform medical and healthcare decisions

AUTHOR: Lewis S.Z., Feinman F., del Aguila M., Newton M., Battista R.J., Shalev E., Kuiper J.
CONFERENCE: 10th Annual Conference on the Science of Dissemination and Implementation in Health
DATE: December 4-6, 2017.
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Impact of Patient Device Experience on Acceptance and Adherence in Diabetes Mellitus

AUTHORS: Liska J., Beaudin M., Rice D., del Aguila M., Murray E., Beal A.
CONFERENCE: European Society for Patient Adeherence, Compliance and Persistence- ESPACOMP 2017
DATE: November 30- December 2, 2017.
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Predictors of Flu Vaccine Uptake in Patients with Diabetes Mellitus

AUTHORS: Liska J., Banyon O., Samson S., Sayre T., Shah R., Beal A.
CONFERENCE: European Society for Patient Adeherence, Compliance and Persistence- ESPACOMP 2017
DATE: November 30- December 2, 2017.
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Transparency Matters: Use of Digital Software Platform in Replicating Published Systematic Literature Reviews and Network Meta-Analyses.

AUTHORS: Husain, F., Kuang, Y., Feinman, T., Whittington, C., Sayre, T., del Aguila, M.
CONFERENCE: ISPOR 20th Annual European Congress.
DATE: November 4-8, 2017.
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Sensitivity Analysis in the Context of Network Meta-Analysis.

AUTHORS: Lewis, S. Z. , Whittington, C., Feinman, T., Shah, R.
CONFERENCE: Guidelines International Network Annual Conference. Philadelphia, PN.
DATE: June 25-27, 2017.
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Term Indexing Technology to Support the Feasibility Assessment of a Benefit-Risk Network Meta-Analysis.

AUTHORS:Snyder, S., Bhattacharya, M., Hendricskon, B., Butylkova, K., Lievano, F., Scarazzini, L.
CONFERENCE: Drug Information Association Annual Meeting, Chicago, IL
DATE: June, 2017
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Terminology Management in Guideline Development: Early Versus Late Binding of Synonyms.

AUTHORS: Whittington, C.J., Lewis, S.Z., Byers, S., Clausel, A., Crumrine, A., Franek, J., Murray, E., Sayre, T., Battista, R., Feinman, T.
CONFERENCE: Guidelines International Network Annual Conference. Philadelphia, PN.
DATE: September 28, 2016.
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Digital Approaches to Analyzing Evidence in Support of Personalized Oncology Guidelines.

AUTHORS: Diekemper, R., Lewis, S.Z.
CONFERENCE: Guidelines International Network Annual Conference. Philadelphia, PN.
DATE: September 28, 2016.
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Medical Terminology Management in Evidence Synthesis: Early Versus Late Binding.

AUTHORS: Whittington, C., Lewis, S.Z., Sayre, T. and Battista, R.
CONFERENCE: AcademyHealth Annual Research Meeting, Boston, MA.
DATE: June 27, 2016.
See presentation

IBM Watson Mega Analytical Database Supports Healthcare Solutions

AUTHORS: Lewis, S.L., Whittington, C., Feinman, T. and Battista, R.
CONFERENCE: 8th Annual Conference on the Science of Dissemination in Health; Co-Hosted by the National Institutes of Health and Academy/Health. Washington, DC.
DATE: Dec 14-15, 2015.
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Technologies That Improve Systematic Reviews: Rapid Reviews Lose Their Appeal.

AUTHOR: Lewis, Sandra Z.
CONFERENCE: Guidelines International Network Annual Conference. Amsterdam, The Netherlands.
DATE: Oct 7-10, 2015.
See presentation

Integrating the Power of Technology into Healthcare System Redesigns for Quality and Patient Care Improvement.

AUTHORS: Lewis, S.L., Whittington, C., Feinman, T. and Battista, R.
CONFERENCE: Concordium 2015. Crystal City, VA.
DATE: September 12-13, 2015.
See poster

Innovative Technology for the Development and Application of Living Evidence-based Guidelines.

AUTHOR: Lewis, Sandra Z.
CONFERENCE: Association for Subscription Agents and Intermediaries Annual. London, UK.
DATE: Feb 16-17, 2015.
See presentation

Systematic Reviews: How Accurate Are They and Can We Do Better?

AUTHORS: Borok, G., Feinman, T. and Tam, I.
CONFERENCE: Guidelines International Network Annual Conference. Melbourne, Australia.
DATE: Aug 20-23, 2014.
See presentation

Using Technology to Increase the Reliability of Systematic Reviews.

AUTHORS: Lewis, S.Z., Borok, G., Feinman, T., Golob, M., and Lawson-Remer, K.
CONFERENCE: Guidelines International Network Annual Conference. Melbourne, Australia.
DATE: Aug 20-23, 2014.
See presentation

Assessing Janus Kinase Inhibitor's Place in Therapy in Established Rheumatoid Arthritis Patients-From a Simplified Indirect Comparison Versus Tumor Necrosis Factor Inhibitors to a Bayesian Probability of Response-The Value of Transparency.

AUTHOR: Ingham, M.P., Song, P., Cartier, S., Lawson-Remer, K. and Murray, E.
CONFERENCE: Academy of Managed Care Pharmacy (AMCP) meeting, San Diego, California.
DATE: October 16-18, 2013.
See presentation

Patient Outcomes of Hip Resurfacing Compared to Total Hip Arthroplasty: A Systematic Review.

AUTHOR: Pykerman, K., Frank, C., Noseworthy, T., Lorenzetti, D., Werle, J., Wasylak, T., Dick, D.A., O'Connor, G. and Marshall, D.
CONFERENCE: ISPOR 18th Annual International Meeting. New Orleans, Louisiana.
DATE: May 18-22, 2013
See presentation

Methods for Comparative Effectiveness Research.

AUTHOR: Wei, W., Frimpter, J., Edwardson, K., Mitchell, D., and Savella, M.G.
CONFERENCE: Society for Medical Decision Making. Phoenix, AZ.
DATE: Oct 17-20, 2012.
See presentation